NOCDURNA is the only rapidly-dissolving sublingual tablet that treats nocturia due to nocturnal polyuria (NP) in adults who wake up at least 2 times per night to urinate

ABOUT NOCDURNA

NOCDURNA is the only rapidly-dissolving sublingual tablet that treats nocturia due to nocturnal polyuria (NP) in adults who wake up at least 2 times per night to urinate.

NOCDURNA is a tablet that dissolves quickly under your tongue

NOCDURNA dissolves in seconds

NOCDURNA is a tablet that dissolves quickly under your tongue—without water.

NOCDURNA imitates a natural hormone in your body called vasopressin (vas-oh-pres-in). This hormone helps the kidneys produce less water at night. If you don’t have enough vasopressin, your kidneys may release too much water at night, causing frequent nighttime urination

How does NOCDURNA work?

NOCDURNA imitates a natural hormone in your body called vasopressin (vas-oh-pres-in).
This hormone helps the kidneys produce less water at night. If you don’t have enough vasopressin, your kidneys may release too much water at night, causing frequent nighttime urination.

NOCDURNA starts working within 30 minutes after you take it.

NOCDURNA is proven to reduce nighttime urination by nearly half, meaning you may wake up fewer times during the night to use the bathroom.  In clinical trials of adults 18 and older, NOCDURNA was studied up to 3 years

Can NOCDURNA help me?

NOCDURNA is proven to reduce nighttime urination by nearly half, meaning you may wake up fewer times during the night to use the bathroom.*

In clinical trials of adults 18 and older, NOCDURNA was studied up to 3 years.

Nocturnal polyuria (NP) can be present in the majority of men and women with OAB or BPH. NOCDURNA has been studied in patients taking medications for OAB or BPH, including antimuscarinics and α-blockers

If I am being treated with medications for OAB or BPH, can I still have NP?

Yes. NP is present in the majority of men and women with OAB or BPH. NOCDURNA has been studied in patients taking medications for OAB or BPH, including antimuscarinics and α-blockers.

  1. Clinical trials demonstrated a reduction of 1.5 nocturnal voids in women (n=118) and 1.3 nocturnal voids in men (n=102) relative to mean baseline. (The mean baseline was 2.9 for women and 3.0 for men.) 78% of women and 67% of men achieved a 33% reduction in mean number of nocturnal voids over a 3-month period compared to baseline.

DOSAGE & ADMINISTRATION

NOCDURNA offers specific doses for men and women.

NOCDURNA offers specific doses for men: 55.3 mcg per day

MEN
55.3 mcg/day

NOCDURNA offers specific doses for women: 27.7 mcg per day

WOMEN
27.7 mcg/day

NOCDURNA (desmopressin acetate) sublingual tablets for nocturnal polyuria

Packaging is not actual size.

Taking NOCDURNA

Take 1 tablet daily, 1 hour before bedtime, without water. Tablet should be kept under the tongue until it has fully dissolved

Take 1 tablet daily, 1 hour before bedtime, without water.
Tablet should be kept under the tongue until it has fully dissolved.

When Taking NOCDURNA

  • Limit the amount of water or liquids you drink from 1 hour before taking NOCDURNA and for 8 hours after taking it
  • Avoid drinks containing caffeine or alcohol before bedtime
  • Empty your bladder immediately before bedtime
 Limit the amount of water or liquids you drink from 1 hour before taking NOCDURNA and for 8 hours after taking it. Avoid drinks containing caffeine or alcohol before bedtime. Empty your bladder immediately before bedtime

WHEN STARTING NOCDURNA

Your doctor should monitor the sodium levels in your blood while you’re taking NOCDURNA. If you are over the age of 65 or at risk for low sodium levels, or take certain medicines that increase your risk, you may need more frequent monitoring.†‡

The sodium levels in your blood should be checked at these timepoints:

BEFORE

STARTING OR RESUMING THERAPY

1 week

within 1 week of starting or resuming therapy

1 month

within 1 month of starting or resuming therapy

periodically

as instructed by your doctor

  1. Patients 65 or older and those at increased risk for low sodium levels or who take certain medicines that increase the risk for hyponatremia should be checked more often. NOCDURNA may need to be stopped temporarily or permanently if you develop hyponatremia, and treatment for hyponatremia started depending on clinical circumstances, including how long the hyponatremia lasts and how serious it is.
  2. NOCDURNA may cause serious side effects, including low levels of sodium in your blood (hyponatremia) which may be life threatening, causing seizures, coma, trouble breathing, or death if not treated early.